Skip to product information
1 of 16

Frontline Plus for Medium Dogs 23 to 44 lbs Flea and Tick Treatment

Frontline Plus for Medium Dogs 23 to 44 lbs Flea and Tick Treatment

Regular price $33.90
Regular price $44.99 Sale price $33.90
Sold out
21 people are viewing this right now
Please Choose Pack Size

Shipping & Returns

Free USA Shipping on Orders Over $120

We ship all US domestic orders within 1-3 business days

Returns & Refunds Policy

30-Day Return Policy

We offer a 30-day return policy from the date of delivery.

To qualify for a return:


  • The item must be unused

  • The item must be in original packaging

  • Proof of purchase is required

Non-Returnable Items

The following items cannot be returned:


  • Opened pet food or treats

  • Personalized products

  • Clearance or final sale items

  • Hygiene-related pet products

Damaged or Incorrect Items

If you receive a damaged or incorrect product:


  1. Contact us within 72 hours of delivery

  2. Provide photos of the product and packaging

  3. We will arrange a replacement or full refund

Return Shipping


  • If the return is due to our error (damaged or incorrect item), we cover return shipping

  • If the return is due to customer preference, the customer pays return shipping

Refund Processing

Once we receive and inspect the returned item:


  • Refunds will be issued to the original payment method

  • Processing time: 5–10 business days
View full product details

Frontline Plus Medium Dogs 23–44 lbs Flea & Tick Treatment is a reliable monthly solution made to protect medium-sized dogs from fleas, ticks, and chewing lice. If your dog weighs between 23 and 44 lbs, this formula gives the right level of protection to keep pests away and your pet comfortable.

Fleas and ticks are more than just annoying. They can cause itching, skin irritation, and even spread diseases. That’s why many dog owners trust Frontline Plus as part of their regular pet care routine. With its waterproof formula and long-lasting results, this treatment helps keep your dog protected for a full month with just one easy application.

Why Pet Owners Choose Frontline Plus for Medium Dogs

When it comes to flea and tick control, consistency matters. Frontline Plus makes it simple to protect your dog without complicated routines.

Here’s what makes it a popular choice:

  • Kills adult fleas, flea eggs, and flea larvae
  • Helps break the flea life cycle and stop infestations
  • Provides protection against ticks and chewing lice
  • Works for up to 30 days with one application
  • Waterproof formula stays effective after bathing or swimming
  • Easy-to-use topical treatment
  • Designed specifically for medium dogs 23–44 lbs

Many pet owners notice fewer fleas and less scratching after regular monthly use.

How Frontline Plus Works

Frontline Plus uses a dual-action formula that targets fleas at different stages of their life cycle. This is important because killing adult fleas alone isn’t enough to stop an infestation.

It contains two key ingredients:

  • Fipronil helps kill adult fleas and ticks quickly after contact.
  • (S)-Methoprene stops flea eggs and larvae from growing into adult fleas.

Once applied, the solution spreads through your dog’s natural skin oils and covers the body from head to tail. It collects in the oil glands and keeps releasing protection over time, which is why it continues working for a full month.

  • 5 stars: 41 (91%)
  • 4 stars: 4 (9%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
S
Stephanie

Frontline Plus has been a convenient option for my 23 to 44 pound dog. The individual tubes are easy to handle and there’s no need to measure the product myself. I also like the straightforward design because it reduces the chance of making a mess.

B
Brandon

My dog didn’t seem bothered after application. I can’t say it has completely eliminated every pest concern, but it has been useful as part of our regular preventative care.

K
Kimberly

I purchased Frontline Plus for my dog because I wanted something easy to include in our monthly routine. The applicator design is handy and the liquid was easy to apply directly to the recommended area.

J
Jason

This treatment was simple to use and didn’t take much time. I applied it according to the instructions, and my dog seemed comfortable afterward. The packaging is compact and the doses are clearly separated, which I appreciate. I’ve noticed fewer signs of flea activity since starting it.

R
Rachel

I’ve found Frontline Plus quite convenient for my medium sized dog. The individual applicator makes it easy to apply without measuring anything, and the instructions are straightforward.

C
Caleb

So far, this flea and tick treatment has worked well for my dog. What I like most is the simple application process and compact packaging, which makes it easy to store. I haven’t had any trouble using the applicator, and the routine doesn’t take much time.

G
Grace

I’m pleased with how straightforward this treatment is to use. The packaging gives clear instructions, and the individual dose is convenient because there’s no measuring involved.

N
Nathan

I bought this after looking for an easy monthly flea and tick treatment for my medium sized dog. Applying it took only a few minutes, which was helpful because my dog doesn’t like sitting still for long.

C
Chloe

This has been a useful addition to my dog’s regular care routine. I like that the treatment doesn’t require complicated preparation, and the individual application makes it easy to keep track of doses.

L
Liam

I’ve found this treatment very convenient for keeping my dog’s flea and tick routine simple. The applicator is easy to handle, and the dose is straightforward to apply without much mess. Since using it regularly, I’ve been happy with the overall flea control.

B
Barrington

I’ve had a good overall experience with this flea and tick treatment. The application process is simple, and I like the fact that each dose comes separately packaged. It saves me from having to measure or mix anything.

A
Angford

Frontline Plus has been a convenient choice for my dog. I like that the treatment is designed specifically for the medium weight range, so I didn’t have to guess which version to buy.

M
Mckinley

I purchased this after wanting something that could help protect my dog from common flea and tick problems. The application was quick, and I didn’t have trouble opening or using the treatment.

D
Derek

What I like most about Frontline Plus is how easy it is to use. The individual treatment makes it simple to apply without measuring anything. My dog is around the 30-pound range, so the medium-dog size fits well.

M
Megan

I’ve been using Frontline Plus for my medium-sized dog for a while now, and the application is pretty straightforward. I like that it covers both fleas and ticks, which makes it convenient for regular protection.

D
Donovan

I purchased this because I wanted a convenient treatment for my medium-sized dog. The packaging was in good condition, and the application process was less complicated than I expected.

M
Marshall

This was easy to incorporate into our regular pet-care routine. The instructions were clear, and I had no trouble understanding the application process.

B
Brooke

I had a fairly positive experience with this treatment. The application was quick, and I liked that I could easily fit it into my dog’s normal grooming schedule.

T
Trevor

The product arrived well packaged and was easy to handle. I appreciate pet products that keep the application process simple, especially when dealing with a dog that does not like sitting still for long.

N
Natalie

I liked the straightforward approach of this treatment. There are no complicated steps, and the packaging gives the basic information needed for application

J
Jordan

I was mainly looking for a practical flea and tick treatment that would not make pet care more difficult. This one was simple to apply, and the instructions were easy enough to understand.

C
Chloe

This product has been convenient to keep as part of my dog’s regular care routine. I liked that the packaging was neat and easy to store, and the application itself was uncomplicated.

F
Fletcher

What I liked most about this treatment was the simple design. The individual application was easy to handle, and the instructions were not confusing.

M
Madison

The application process was straightforward, and I appreciated not having to spend much time preparing everything. My dog tolerated it well, which made the experience easier. The packaging was secure when it arrived, and the information was clearly presented

C
Calebharrison

I found this treatment quite easy to apply to my dog, and the packaging made the instructions simple to follow. The application did not take much time, which is helpful with an active dog.

O
Olivia Brown

Very practical flea and tick treatment for medium dogs. It’s easy to apply, and keeping track of the monthly treatment fits well into our regular pet-care schedule.

M
Michael Turner

A convenient addition to my dog’s monthly care routine. The applicator is easy to handle, and I like that there’s no need to mix anything with food.

E
Emily Parker

The application process is quick and easy. I appreciate that this version is specifically designed for medium-sized dogs in the 23–44 lb weight range.

D
Daniel Carter

I like how straightforward this treatment is to use. My dog spends a lot of time outdoors, so having a simple topical option makes regular flea and tick prevention easier.

S
Sarah

Easy to apply and convenient for monthly flea and tick protection. The applicator makes the treatment quick and simple to add to my dog’s regular care routine.

M
Moore Adams

Overall, I had a positive experience ordering this product. It was easy to apply, convenient, and arrived without any issues.

K
Kevin Parker

The application was quick and easy, which helps when caring for a big dog. I was happy with the service and delivery time.