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Frontline Plus for Large Dogs 45-88 lbs Flea Tick Treatment and Lice Control

Frontline Plus for Large Dogs 45-88 lbs Flea Tick Treatment and Lice Control

Regular price $27.49
Regular price $44.99 Sale price $27.49
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Shipping & Returns

Free USA Shipping on Orders Over $120

We ship all US domestic orders within 1-3 business days

Returns & Refunds Policy

30-Day Return Policy

We offer a 30-day return policy from the date of delivery.

To qualify for a return:


  • The item must be unused

  • The item must be in original packaging

  • Proof of purchase is required

Non-Returnable Items

The following items cannot be returned:


  • Opened pet food or treats

  • Personalized products

  • Clearance or final sale items

  • Hygiene-related pet products

Damaged or Incorrect Items

If you receive a damaged or incorrect product:


  1. Contact us within 72 hours of delivery

  2. Provide photos of the product and packaging

  3. We will arrange a replacement or full refund

Return Shipping


  • If the return is due to our error (damaged or incorrect item), we cover return shipping

  • If the return is due to customer preference, the customer pays return shipping

Refund Processing

Once we receive and inspect the returned item:


  • Refunds will be issued to the original payment method

  • Processing time: 5–10 business days
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Your dog is more than just a pet, they are part of your family. Keeping them safe from fleas and ticks is essential for their comfort and overall health. Frontline Plus for Large Dogs (45–88 lbs) offers a powerful, vet-trusted solution that not only eliminates parasites but prevents future infestations before they start.

With a single monthly application, you can ensure your dog stays comfortable, active, and itch-free.

Key Benefits at a Glance

  • Comprehensive Protection
    Effectively kills fleas, ticks, flea eggs, larvae, and chewing lice.
  • Breaks the Flea Life Cycle
    Stops infestations at every stage, not just on the surface.
  • Long-Lasting Performance
    Provides up to 30 days of continuous protection.
  • Waterproof Reliability
    Maintains effectiveness after bathing, swimming, or rain exposure.
  • Effortless Application
    Simple, mess-free topical treatment applied in seconds.

Advanced Dual-Action Formula

Frontline Plus is formulated with two powerful ingredients that work together for complete protection:

  • Fipronil targets and eliminates adult fleas and ticks on contact.
  • (S)-methoprene prevents flea eggs and larvae from developing.

This dual-action approach ensures your dog is protected not only today, but also in the weeks ahead by stopping the cycle of reinfestation.

Why Choose Frontline Plus?

Frontline Plus has earned the trust of pet owners worldwide for its consistent performance and proven results. It is ideal for dogs that:

  • Spend time outdoors
  • Live in multi-pet households
  • Are exposed to flea and tick-prone environments

Its reliability and ease of use make it a go-to solution for long-term parasite prevention.

  • 5 stars: 22 (96%)
  • 4 stars: 1 (4%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
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Isabella

I was pleased with how straightforward this product was to use on my dog. The treatment comes in an easy-to-handle format, and I didn't need much time to apply it. The box also clearly identifies the appropriate dog size, which helped avoid confusion when ordering.

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Ryan

The main thing I like about this treatment is the convenience. Having flea, tick, and lice control included means I don't have to keep track of several different products. The packaging was neat and the instructions were clearly presented. It is also easy to store between applications.

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Natalie

I bought this after looking for a flea and tick treatment suitable for my dog's weight range. The application was less complicated than I expected, and the instructions were easy to understand.

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Marcus

This has been a practical addition to my dog's regular care routine. The individual application was quick and didn't require much preparation. I appreciated the straightforward packaging because it made it easy to identify the product for large dogs.

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Chloe

I found this treatment quite easy to apply, which is important with a larger dog that does not like sitting still for long. The packaging was clear, and the instructions were simple to follow.

M
Megan Brooks

Excellent option for extra-large breeds. My dog enjoys running through wooded areas, and this treatment has helped keep pests under control.

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Rachel Kim

We've used all three doses over the past few months, and the results have been consistent. It's become part of our regular pet care routine.

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Rachel Kim

We've used all three doses over the past few months, and the results have been consistent. It's become part of our regular pet care routine.

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Tyler Morgan

This has worked well for my 120-lb Mastiff. The protection lasted the full month, and I plan to keep using it year-round.

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Jasminecole

I appreciate how simple it is to apply. It dries fairly quickly, and my dog returned to normal activities without any issues.

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Conno rhayes

After the first application, I noticed a clear improvement. My dog stopped scratching as much, and I haven't found any ticks after our walks.

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Emily Ross

Great value for a three-month supply. The instructions were easy to follow, and my Saint Bernard stayed comfortable throughout the season.

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Graceturner

Highly satisfied with this purchase. It's simple to use, effective, and gives me confidence that my dog is protected every month.

L
Lucas Parker

Works well for my 55-lb mixed breed. No greasy residue after it dried, and I haven't seen any ticks during our hikes.

A
Ava Mitchell

I've tried several flea treatments, and this one has given the best results so far. My dog hasn't had any problems since switching.

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Noah Simmons

Reliable flea and tick protection for my German Shepherd. The product is easy to apply and lasts the full month.

C
Chloe Bennett

Good quality product that has kept my dog comfortable during flea season. I will definitely continue purchasing it.

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Liam Foster

This treatment worked exactly as expected. I noticed a big reduction in fleas within a couple of days after application.

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Olivia hayes

Great monthly flea and tick prevention. My Labrador spends a lot of time outdoors, and this product has provided reliable protection.

M
Mason reed

Very easy to use. The application took only a minute, and my dog experienced no irritation. Happy with the results.

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Sophia Carter

I've been using this for several months, and it has worked consistently. My dog hasn't had any flea issues since starting this treatment.

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Ethan

Excellent product! I used it on my 70-lb Golden Retriever, and it kept fleas and ticks away for the entire month. Easy to apply and worth the price.

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Olivia White

Great prices and genuine Frontline Plus. My dog is finally flea-free again.