• Frontline Plus for Large Dogs
  • Frontline Plus for Large Dogs
  • Frontline Plus for Large Dogs
  • Frontline Plus for Large Dogs
  • Frontline Plus for Large Dogs
  • Frontline Plus for Large Dogs
  • Frontline Plus for Large Dogs
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Frontline Plus for Large Dogs 45-88 lbs Flea Tick Treatment and Lice Control

Frontline Plus for Large Dogs 45-88 lbs Flea Tick Treatment and Lice Control

$27.49
$44.99 $27.49
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Shipping & Returns

Free USA Shipping on Orders Over $120

We ship all US domestic orders within 1-3 business days

Returns & Refunds Policy

30-Day Return Policy

We offer a 30-day return policy from the date of delivery.

To qualify for a return:


  • The item must be unused

  • The item must be in original packaging

  • Proof of purchase is required

Non-Returnable Items

The following items cannot be returned:


  • Opened pet food or treats

  • Personalized products

  • Clearance or final sale items

  • Hygiene-related pet products

Damaged or Incorrect Items

If you receive a damaged or incorrect product:


  1. Contact us within 72 hours of delivery

  2. Provide photos of the product and packaging

  3. We will arrange a replacement or full refund

Return Shipping


  • If the return is due to our error (damaged or incorrect item), we cover return shipping

  • If the return is due to customer preference, the customer pays return shipping

Refund Processing

Once we receive and inspect the returned item:


  • Refunds will be issued to the original payment method

  • Processing time: 5–10 business days
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Your dog is more than just a pet, they are part of your family. Keeping them safe from fleas and ticks is essential for their comfort and overall health. Frontline Plus for Large Dogs (45–88 lbs) offers a powerful, vet-trusted solution that not only eliminates parasites but prevents future infestations before they start.

With a single monthly application, you can ensure your dog stays comfortable, active, and itch-free.

Key Benefits at a Glance

  • Comprehensive Protection
    Effectively kills fleas, ticks, flea eggs, larvae, and chewing lice.
  • Breaks the Flea Life Cycle
    Stops infestations at every stage, not just on the surface.
  • Long-Lasting Performance
    Provides up to 30 days of continuous protection.
  • Waterproof Reliability
    Maintains effectiveness after bathing, swimming, or rain exposure.
  • Effortless Application
    Simple, mess-free topical treatment applied in seconds.

Advanced Dual-Action Formula

Frontline Plus is formulated with two powerful ingredients that work together for complete protection:

  • Fipronil targets and eliminates adult fleas and ticks on contact.
  • (S)-methoprene prevents flea eggs and larvae from developing.

This dual-action approach ensures your dog is protected not only today, but also in the weeks ahead by stopping the cycle of reinfestation.

Why Choose Frontline Plus?

Frontline Plus has earned the trust of pet owners worldwide for its consistent performance and proven results. It is ideal for dogs that:

  • Spend time outdoors
  • Live in multi-pet households
  • Are exposed to flea and tick-prone environments

Its reliability and ease of use make it a go-to solution for long-term parasite prevention.