• Advantage II Lage Dog
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Advantage II for Large Dogs 21–55 lbs Flea Treatment 6 Monthly Doses Fast Acting

Advantage II for Large Dogs 21–55 lbs Flea Treatment 6 Monthly Doses Fast Acting

$60.70
$75.99 $60.70
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Shipping & Returns

Free USA Shipping on Orders Over $120

We ship all US domestic orders within 1-3 business days

Returns & Refunds Policy

30-Day Return Policy

We offer a 30-day return policy from the date of delivery.

To qualify for a return:


  • The item must be unused

  • The item must be in original packaging

  • Proof of purchase is required

Non-Returnable Items

The following items cannot be returned:


  • Opened pet food or treats

  • Personalized products

  • Clearance or final sale items

  • Hygiene-related pet products

Damaged or Incorrect Items

If you receive a damaged or incorrect product:


  1. Contact us within 72 hours of delivery

  2. Provide photos of the product and packaging

  3. We will arrange a replacement or full refund

Return Shipping


  • If the return is due to our error (damaged or incorrect item), we cover return shipping

  • If the return is due to customer preference, the customer pays return shipping

Refund Processing

Once we receive and inspect the returned item:


  • Refunds will be issued to the original payment method

  • Processing time: 5–10 business days
View full product details

Advantage II Large Dog Flea Treatment 6 Doses (21–55 lbs) is a fast-acting topical flea control designed to kill fleas at all life stages. This monthly treatment eliminates adult fleas, eggs, and larvae, helping stop infestations and prevent re-infestation.

Each pack contains 6 easy-to-apply doses, providing up to 6 months of flea protection for dogs weighing 21–55 lbs. The formula starts working within 12 hours and remains effective for 30 days per treatment.

Key Benefits

  • Kills adult fleas, eggs, and larvae
  • Starts working within 12 hours
  • Provides 30-day protection per dose
  • Includes 6 monthly doses
  • Helps prevent flea re-infestation
  • Kills chewing lice.
  • Waterproof after 24 hours.
  • Easy topical application

Product Details

Product Name: Advantage II Large Dog Flea Treatment
Dog Weight Range: 21–55 lbs
Pack Size: 6 Doses
Application Type: Topical Spot-On
Protection Duration: Up to 30 Days per Dose
Suitable Age: Dogs and Puppies 7 Weeks or Older
Target Parasites: Fleas and Chewing Lice

How to Use

  1. Apply one tube to dry skin along the dog’s back.
  2. Use once every 30 days.
  3. Avoid bathing your dog for 24 hours after application.

Why Choose Advantage II Large Dog Flea Treatment?

Advantage II flea treatment for large dogs offers dependable monthly protection with a simple topical application. It kills fleas quickly, prevents future infestations, and helps keep your dog comfortable and flea-free.
  • 5 stars: 8 (100%)
  • 4 stars: 0 (0%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
L
Lauren Davis

Convenient packaging and easy application. Having six doses available makes it much easier to maintain a regular schedule.

K
Kevin Adams

This product has made our monthly flea-care routine much easier. No pills or complicated steps are involved.

R
Ryan Foster

Very easy to use and convenient for keeping up with monthly flea treatment.

J
Jessica Morgan

I prefer topical treatments, and this one is simple to apply. The six-month supply is especially convenient.

M
Michael Turner

Great option for my large dog. The applicator is easy to use and the treatment fits nicely into our regular pet-care routine.

S
Sarah Mitchell

The monthly application is very convenient. I appreciate having six doses ready so I don’t have to reorder every month.

D
Daniel Brooks

I really like how straightforward this treatment is. Application takes only a few minutes and fits easily into our routine.

E
Emily Carter

Easy to apply and convenient for monthly flea protection. The six-dose pack makes it simple to stay on schedule.